958-100 Myocardial Preconditioning During Repeated Daily Ischemic Episodes

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Ischemic Preconditioning Increases Myocardial Tolerance to Subsequent Ischemic Episodes

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Cardiac adaptation to ischemia. Ischemic preconditioning increases myocardial tolerance to subsequent ischemic episodes.

It has long been recognized that a brief episode of myocardial ischemia causes reversible myocyte injury, "reversible" being defined by the fact that early restoration of arterial flow prevents infarction and permits eventual restoration of normal myocardial structure, function, and metabolism. However, numerous studies during the last 15 years1-5 have revealed that complete recovery is not imm...

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Myocardial apoptosis and ischemic preconditioning.

Necrosis and apoptosis are two forms of cell death in the myocardium that have been associated with ischemia and reperfusion. Although it has been well documented that necrosis, as a major form of myocyte cell death, rapidly leads to a destruction of a large group of cells after myocardial ischemia and reperfusion, the induction of apoptosis in myocardium, primarily triggered during reperfusion...

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Ischemic Preconditioning During Coronary

Background Brief episodes of ischemia render the heart more resistant to subsequent ischemia; this phenomenon has been called ischemic preconditioning. In some animal species, myocardial preconditioning appears to be due to activation of ATP-sensitive K' (KATP) channels. The role played by KATP channels in preconditioning in humans remains unknown. The aim of this study was to establish whether...

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Investigating the role of acute and repeated stress on remote ischemic preconditioning-induced cardioprotection

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 1995

ISSN: 0735-1097

DOI: 10.1016/0735-1097(95)92330-8